1 Samuel 6:5

5“In accord with the number of the provinces of the Philistines, you shall fashion five gold cysts and five gold mice. For the same plague has been upon all of you and your princes. And you shall fashion a likeness of your cysts and a likeness of the mice, which have destroyed the land. And so shall you give glory to the God of Israel, so that perhaps he may lift off his hand from you, and from your gods, and from your land.
6:5The word ‘anos’ can refer to the anus, but it can also refer to piles or hemorrhoids, i.e. to swellings in that area of the body. In this context, the term refers to the cysts or pustules that occurred as a result of the disease which was plaguing the Philistines.(Conte)
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