Ephesians 6:12

For we wrestle. Fights then were a hand to hand grapple.

Not against flesh and blood. While flesh and blood may seem to assail us, the real enemies are evil spiritual powers.

Against principalities, against powers. These terms designate different rank of evil spirits. These were fallen angels (see Ro 8:38). The same terms are applied to the different ranks of holy angels in Eph 1:21.

Against the rulers of the darkness of this world. Satan is described as the ruler of this world (Joh 12:31 14:30 16:11) and the god of this world (2Co 4:4). He uses for his dominion not only evil spirits, but wicked men, and his sway is darkness rather than light.

Against spiritual wickedness in high [places]. "Spiritual [hosts] of wickedness" (Revised Version). It is likely that the meaning is the same as in Eph 2:2 The high places, the air, is a dwelling place and medium of these evil influences.
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